Pharmaceutical compositions of varenicline

Details Pharmaceutical compositions of varenicline Pharmaceutical compositions of varenicline

A - Human Necessities

61

K

A61K 31/4995 (2006.01) A61P 25/34 (2006.01)

Patent

CA 2525874

The invention relates to novel pharmaceutical dosage forms of varenicline, which are useful for aiding smoking cessation and which have good storage stability. In particular, the present invention relates to formulations of varenicline wherein the dosage forms that are produced therefrom generate under specified storage conditions less than about 4% on a weight basis of the N-formyl and N-methyl degradation products.

L'invention se rapporte à de nouvelles formes pharmaceutiques de varenicline permettant d'aider une personne à arrêter de fumer et qui présentent une bonne stabilité en stockage. En particulier, la présente invention se rapporte à des formulations de varenicline dans lesquelles les formes pharmaceutiques obtenues engendrent, dans des conditions de stockage données, moins de 4 % en poids environ de produits de dégradation à base de N-formyle et N-méthyle.

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