Method for diagnosing testicular seminomas

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2500982

Objective methods for detecting and diagnosing testicular seminoma (TS) are described herein. In one embodiment, the diagnostic method involves the determining a expression level of TS -associated gene that discriminate between TS and nomal cell. The present invention further provides methods of screening for therapeutic agents useful in the treatment of TS, methods of treating TS and method of vaccinating a subject against TS.

La présente invention concerne des méthodes permettant de détecter et de diagnostiquer un séminome du testicule (ST). Dans un mode de réalisation, la méthode diagnostique consiste à déterminer un niveau d'expression du gène associé au séminome du testicule, lequel niveau permet de différencier un séminome du testicule d'une cellule normale. Cette invention concerne également des méthodes permettant de cribler des agents thérapeutiques utiles dans le traitement du séminome du testicule; des méthodes permettant de traiter le séminome du testicule et une méthode permettant de vacciner un sujet contre le séminome du testicule.

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