A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/66 (2006.01) A61K 31/675 (2006.01)
Patent
CA 2321864
Drugs effective in the prevention and treatment of diseases due to abnormal production of interleukin-6, which are interleukin-6 production inhibitors containing as the active ingredient methanebis-phosphonic acid derivatives and exhibit an inhibitory effect against the production of interleukin-6. These drugs can be expected to be effective in the prevention and treatment of diseases in which interleukin-6 participates, for example, thrombocytosis, inflammatory diseases, immune response disorders, osteoporosis, rheumatoid arthritis, hypercalcemia, multiple myeloma, cachexia and nephritis.
L'invention concerne des médicaments utilisés dans la cadre de la prévention et du traitement de maladies dues à une production anormale d'interleukine-6. Ces médicaments sont des inhibiteurs de la production d'interleukine-6, qui renferment, comme principe actif, des dérivés d'acide méthanebisphosphonique, et qui ont un effet inhibiteur vis-à-vis de la production d'interleukine-6. Ces médicaments peuvent être efficaces dans le cadre de la prévention et du traitement de maladies faisant intervenir l'interleukine-6, notamment la thrombocytose, les maladies inflammatoires, les dysfonctionnements de la réponse immunitaire, l'ostéoporose, la polyarthrite rhumatoïde, l'hypercalcémie, le myélome multiple, la cachexie et la néphrite.
Funaba Yuriko
Ito Masatoshi
Koike Junzo
Okazaki Seiji
Tanahashi Masahiko
Smart & Biggar
Toray Industries Inc.
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