C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) C07K 14/195 (2006.01) C07K 14/315 (2006.01) C07K 16/12 (2006.01) C12N 1/21 (2006.01) C12N 15/65 (2006.01) C12Q 1/18 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01)
Patent
CA 2152066
The invention relates to a protein VanB involved, in Gram-positive bacteria, in resistance to glycopeptides, particularly to vancomycine, said resistance being of the type inducible by the vancomycine and non-inducible by teicoplanine. The invention also relates to the utilisation of fragments of nucleotides of the gene v &cir& _a &cir& _n &cir& _ B for the detection of resistances to glycopeptides.
L'invention concerne une protéine VanB impliquée chez des bactéries à Gram- positif, dans une résistance à des glycopeptides, en particulier à la vancomycine, cette résistance étant de type inductible par la vancomycine et non inductible par la teicoplanine. L'invention vise aussi 1'utilisation de fragments de nucléotides du gène van B pour la détection de résistances à des glycopeptides.
Arthur Michel
Courvalin Patrice
Dutka-Malen Sylvie
Evers Stefan
Fetherstonhaugh & Co.
Institut Pasteur
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