Method for diagnosing alzheimer's disease

G - Physics – 01 – N

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G01N 33/20 (2006.01) G01N 33/68 (2006.01) G01N 33/487 (2006.01)

Patent

CA 2308371

A method is provided for diagnosing Alzheimer's disease using human blood platelets wherein the presence or absence of functioning calcium-dependent potassium channels in blood platelets are determined by employing potassium channel blockers such as apamin or charybdotoxin, the absence of functioning calcium-dependent potassium channels indicating a positive diagnosis for Alzheimer's disease.

On décrit un procédé qui permet de diagnostiquer la maladie d'Alzheimer au moyen de plaquettes de sang humain dans lesquelles la présence ou l'absence de canaux potassium fonctionnels dépendant du calcium est déterminée par l'emploi d'inhibiteurs de canal potassium, tels que l'apamine ou la charybdotoxine, l'absence de canaux potassium fonctionnels dépendant du calcium indiquant un diagnostic positif de la maladie d'Alzheimer.

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