Process for preparing forms of atorvastatin calcium...

C - Chemistry – Metallurgy – 07 – D

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C07D 493/04 (2006.01)

Patent

CA 2579997

The preparation of atorvastatin calcium epoxide dihydroxy (AED) is described. AED can be used as a standard or marker in determining the amount of AED in a sample. AED can therefore be used as a tool in preparing atorvastatin calcium substantially free of AED.

L'invention concerne la préparation de dihydroxy époxidique d'atorvastatine calcique (AED). L'AED peut être utilisé en tant que norme ou marqueur pour déterminer la quantité d'AED dans un échantillon. L'AED peut par conséquent être utilisé comme outil dans la préparation d'atorvastatine calcique sensiblement exempte d'AED.

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