Compositions and methods for systemic delivery of oral...

A - Human Necessities – 61 – K

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A61K 39/08 (2006.01) A61K 47/48 (2006.01) C07K 14/33 (2006.01)

Patent

CA 2306995

Compositions and methods of oral delivery of an antigen or therapeutic agent to the general circulation using a modified botulinum toxin which is capable of translocating from the gut to the general circulation but which is altered to be nontoxic are provided.

Cette invention se rapporte à des compositions et à des procédés d'administration par voie orale d'un antigène ou d'un agent thérapeutique dans la circulation générale, au moyen d'une toxine de botulinum modifiée qui est capable de passer de l'intestin dans la circulation générale, et qui est modifiée pour être non toxique.

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