C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/20 (2006.01) A61K 39/102 (2006.01) A61K 39/295 (2006.01) C07K 14/285 (2006.01) C12N 1/21 (2006.01) C12N 1/36 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2206575
The present invention relates to live attenuated RTX-toxin producing bacteria of the family Pasteurellaceae, of which the attenuation is due to the fact that they produce RTX toxin in a non-activated form. The invention also relates to vaccines for the protection of mammals against infection with RTX-toxin producing bacteria of the family Pasteurellaceae, and to methods for the preparation of said live attenuated bacteria and vaccines.
Bactéries vivantes atténuées de la famille des Pasteurellaceae produisant des toxines RTX; l'atténuation est due au fait que ces bactéries produisent des toxines RTX sous une forme non activée. L'invention concerne également des vaccins destinés à protéger les mammifères contre l'infection par les bactéries de la famille des Pasteurellaceae produisant des toxines RTX, de même que le mode de préparation desdites bactéries et vaccins vivants atténués.
Frey Joachim
Segers Ruud Philip Antoon Maria
Van Den Bosch Johannes Franciscus
Akzo Nobel Nv
Fetherstonhaugh & Co.
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