Iodinated benzoyl acetals and ketals

Details Iodinated benzoyl acetals and ketals Iodinated benzoyl acetals and ketals

C - Chemistry, Metallurgy

07

C

C07C 233/54 (2006.01) A61K 49/04 (2006.01) C07C 235/06 (2006.01)

Patent

CA 2107723

IODINATED BENZOYL ACETALS AND KETALS ABSTRACT Compounds having the structure Image wherein (Z?COO is the residue of an iodinated aromatic acid; R is alkyl, cycloalkyl, aryl, aralkyl, Image , Image , or alkenyl; R1 is H, alkyl, cycloalkyl, aryl, aralkyl, or ?CH2?mCO2R3; R2 is H, alkyl, cycloalkyl, aryl, aralkyl, ?CH2?nCO2R4, or a Image group, wherein Z, R and R1 are as defined above; or R1 and R2, taken together with the carbon atom to which they are attached represent cycloalkyl; R3 is H, alkyl, cycloalkyl, aryl or aralkyl; R4 is H, alkyl, cycloalkyl, aryl or aralkyl; and m, n and p are independently an integer of from 0 to 17; provided that R1 and R2 can not both be H; are useful in the preparation of x-ray contrast compositions for medical imaging.

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