Methods of cancer treatment using naaladase inhibitors

Details Methods of cancer treatment using naaladase inhibitors Methods of cancer treatment using naaladase inhibitors

A - Human Necessities

61

K

A61K 31/66 (2006.01) A61K 31/00 (2006.01) A61K 31/665 (2006.01) A61K 31/67 (2006.01) A61K 31/675 (2006.01) A61K 38/05 (2006.01) A61K 38/06 (2006.01) A61K 45/06 (2006.01) C07F 9/30 (2006.01) C07F 9/38 (2006.01)

Patent

CA 2257433

The present disclosure relates to dipeptidase inhibitors, and more particularly, to novel methods of using phosphonate derivatives, hydroxyphosphinyl derivatives, and phosphoramidate derivatives to inhibit N- Acetylated .alpha.-Linked Acidic Dipeptidase (NAALADase) enzyme activity, and to treat prostate diseases, especially using the compounds of the present invention for the inhibition of the growth of prostate cancer cells.

La présente invention concerne des inhibiteurs de la dipeptidase, et plus particulièrement, de nouvelles méthodes d'utilisation des dérivés phosphonate, des dérivés hydroxyphosphinyle, et des dérivés phosphoramidate pour inhiber l'activité de la dipeptidase acide à liaison .alpha.N-acétylée (NAALADase), et pour traiter les affections de la prostate, notamment à l'aide des composés de la présente invention pour inhiber la croissance des cellules cancéreuses de la prostate.

Affiliated with

Also associated with

Rating

Methods of cancer treatment using naaladase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Methods of cancer treatment using naaladase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods of cancer treatment using naaladase inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1460964