Quinazoline derivatives which promote the release of...

Details Quinazoline derivatives which promote the release of... Quinazoline derivatives which promote the release of...

C - Chemistry, Metallurgy

07

D

C07D 417/06 (2006.01) A61K 31/136 (2006.01) A61K 31/517 (2006.01) A61P 5/18 (2006.01) A61P 19/08 (2006.01) A61P 19/10 (2006.01) C07D 213/38 (2006.01) C07D 213/88 (2006.01) C07D 239/74 (2006.01) C07D 239/78 (2006.01) C07D 239/82 (2006.01) C07D 239/84 (2006.01) C07D 239/93 (2006.01) C07D 265/36 (2006.01) C07D 401/06 (2006.01) C07D 401/08 (2006.01) C07D 401/12 (2006.01) C07D 403/06 (2006.01) C07D 403/10 (2006.01) C07D 403/12 (2006.01) C07D 405/06 (2006.01) C07D 405/12 (2006.01) C07D 417/08 (2006.01)

Patent

CA 2449234

Use of compound of formula (I), wherein (a) is (b) or (c) and wherein the symbols are as defined, or a pharmaceutically-acceptable and-cleavable ester, or acid addition salt thereof, for the preparation of a medicament for promoting the release of parathyroid hormone, e.g. for preventing or treating bone conditions which are associated with increased calcium depletion or resorption or in which stimulation of bone formation and calcium fixation in the bone is desirable.

La présente invention concerne un composé de formule (I), dans laquelle (a) est (b) ou (c) et dans laquelle les symboles sont tels que définis dans la description, ou un ester pharmaceutiquement acceptable et clivable, ou son sel d'addition à un acide, pour la préparation d'un médicament favorisant la libération de l'hormone parathyroïdienne, par exemple pour la prévention ou le traitement de conditions osseuses qui sont associées à une déplétion ou une résorption calcique accrue ou dans lesquelles une stimulation de la formation osseuse et de la fixation calcique dans les os est souhaitable.

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