Iodinated aromatic compounds

Details Iodinated aromatic compounds Iodinated aromatic compounds

C - Chemistry, Metallurgy

07

C

C07C 233/54 (2006.01) A61K 49/04 (2006.01) C07C 233/88 (2006.01) C07C 235/46 (2006.01) C07C 255/55 (2006.01) C07C 275/34 (2006.01) C07C 309/42 (2006.01) C07C 311/29 (2006.01) C07D 213/60 (2006.01) C07D 215/16 (2006.01) C07D 239/28 (2006.01) C07D 307/56 (2006.01) C07D 333/26 (2006.01)

Patent

CA 2102269

- 0 - ABSTRACT Compounds having the structure Image wherein (Z?COO is the residue of an iodinated aromatic acid; n is an integer from 0 to 6; R1 and R2 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy or aryloxy; R3 and R4 are independently H, alkyl, fluoroalkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, halogen, hydroxy or acylamino; Q represents the atoms necessary to complete a carbocyclic or heterocyclic unsaturated mono- or bicyclic aromatic ring; and R5 is H, alkyl, cycloalkyl, aryl, aralkyl, alkoxy, aryloxy, halogen, hydroxy, amino, acylamino, alkoxyalkyl, fluoroalkyl, acetamidoalkyl, COO-alkyl, cyano, carboxamido, sulfonate, sulfonamido, ureido, or carbamyl are useful as contrast agents in x-ray imaging compositions and methods.

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