C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 519/00 (2006.01) A61K 31/551 (2006.01) C07D 487/04 (2006.01)
Patent
CA 2615463
Compounds of formula (I): (where variables R2, R7, D, W, X, Y and Z are as described herein) which are antagonists of CGRP receptors and which are useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
La présente invention concerne des composés de formule I : (où les variables R2, R7, D, W, X, Y et Z sont tells que décrites ici) qui sont des antagonistes des récepteurs de CGRP et qui sont utilisés dans la prévention de maladies dans lesquelles le CGRP est impliqué, telles que la migraine. L~invention concerne également des compositions pharmaceutiques comprenant ces composés et l~utilisation de ces composés et de ces compositions dans la prévention ou le traitement de maladies dans lesquelles le CGRP impliqué.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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