Osteogenic devices

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/18 (2006.01) A61K 38/18 (2006.01) A61L 27/00 (2006.01) A61L 27/22 (2006.01) A61L 27/24 (2006.01) A61L 27/34 (2006.01) A61L 27/36 (2006.01) C07K 14/51 (2006.01) C12N 15/63 (2006.01) A61C 8/00 (2006.01) A61F 2/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2042577

-81- Abstract Disclosed are 1) amino acid sequence data, structural features, and various other data characterizing a human osteogenic protein, OP1, 2) osteogenic devices comprising a heat treated xenogenic bone collagen matrix containing osteogenic protein, 3) methods of producing osteogenic proteins using recombinant DNA technology and 4) use of osteogenic devices to mimic the natural course of endochondral bone formation in mammals.

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