Methods and kits for screening nucleic acid duplex stability

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) G01N 1/18 (2006.01) G01N 24/00 (2006.01) G01N 25/20 (2006.01) G01N 31/16 (2006.01)

Patent

CA 2355920

Simple methods and kits for determining the thermodynamic stability of nucleic acid duplexes and single polynucleotide polymorphisms via competitive equilibria are provided.

Cette invention concerne des procédés et des kits simples permettant de déterminer la stabilité thermodynamique de duplex d'acide nucléique et de polymorphismes polynucléotidiques simples via des équilibres concurrentiels.

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