C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/50 (2006.01) C07D 239/48 (2006.01) C07D 401/12 (2006.01) C07D 401/14 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2685402
The present invention relates to novel triaminopyrimidine derivatives of formula (I) in which R1, R2, W, R3, R4, and R5 are variable groups. These products have a Cdc25-phosphatase-inhibiting activity. The invention also relates to a process for synthesizing these compounds and also to therapeutic compositions containing these products and to the use thereof as medicaments.
La présente invention a pour objet de nouveaux dérivés de triamino-pyrimidine de formule (I) dans laquelle R1, R2, W, R3, R4, et R5 sont des groupements variables.formule (I) Ces produits ont une activité inhibitrice de phosphatases Cdc25. L'invention concerne également un procédé de synthèse de ces composés ainsi que des compositions thérapeutiques contenant ces produits et leur utilisation comme médicament.
Bigg Dennis
Liberatore Anne-Marie
Pons Dominique
Prevost Gregoire
Goudreau Gage Dubuc
Ipsen Pharma S.a.s.
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