A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/435 (2006.01) A61K 31/197 (2006.01) A61K 31/426 (2006.01) A61K 31/4425 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2337997
There is disclosed a genus of compounds and pharmaceutical compositions that are protective for mitigating damage associated with tissue ischemia, particularly stroke (CNS ischemia), and ischemia of the myocardium. The present invention further provides a method for treating tissue damage caused by ischemia. Lastly, the present invention provides a method for treating tissue damage caused by providing a compound that inhibits the cytotoxic activity of 3-aminopropanal.
L'invention concerne un genre de composés et de compositions pharmaceutiques qui ont un effet d'atténuation sur les lésions associées à l'ischémie tissulaire, notamment les accidents cérébrovasculaires (ischémie du système nerveux central) et l'ischémie myocardique. L'invention concerne également une méthode de traitement des lésions tissulaires dues à l'ischémie. L'invention concerne enfin une méthode de traitement des lésions tissulaires qui consiste à administrer un composé inhibant l'activité cytotoxique du 3-aminopropanal.
Al-Abed Yousef
Bucala Richard J.
Ivanova Svetlana
Tracey Kevin J.
Mccarthy Tetrault Llp
North Shore-Long Island Jewish Research Institute
The Picower Institute For Medical Research
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