C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/14 (2006.01) A61K 31/505 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01) C07D 403/04 (2006.01) C07D 409/14 (2006.01) C07D 417/04 (2006.01) C07D 471/04 (2006.01) C07D 491/04 (2006.01) C07D 513/04 (2006.01)
Patent
CA 2486530
Compounds of formula (I) are effective for treatment of cell proliferation or apoptosis mediated diseases. The invention encompasses novel compounds and pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving stroke, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes. Formula (I)
L'invention a trait aux composés de formule (I). Ces composés sont efficaces dans le traitement de maladies ayant pour origine une prolifération de cellules ou une apoptose. L'invention a trait à de nouveaux composés et à des dérivés pharmaceutiquement acceptables de ces composés, à des compositions pharmaceutiques et à des méthodes de prophylaxie et de traitement de maladies ou d'états pathologiques tels qu'un accident vasculaire cérébral, un cancer, et similaires. L'invention a trait également à des procédés de production de ces composés ainsi qu'à des intermédiaires utiles dans ces processus.
Huang Qi
Kaller Matthew
Nguyen Thomas
Norman Mark H.
Rzasa Robert
Amgen Inc.
Osler Hoskin & Harcourt Llp
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