Use of a cgrp-antagonist combined with a serotonin-reuptake...

Details Use of a cgrp-antagonist combined with a serotonin-reuptake... Use of a cgrp-antagonist combined with a serotonin-reuptake...

A - Human Necessities

61

K

A61K 31/4178 (2006.01) A61K 31/4196 (2006.01) A61K 31/513 (2006.01) A61K 31/551 (2006.01) A61K 38/05 (2006.01) A61P 25/06 (2006.01)

Patent

CA 2563687

The invention relates to a method for treating or preventing headaches, migraines or cluster headaches. Said method involves the common administration of a therapeutically active amount of a CGRP-antagonist (A) or a physiologically compatible salt thereof, and a therapeutically active amount of a serotonin-reuptake inhibitor (B) or a physiologically compatible salt thereof. The invention also relates to the corresponding pharmaceutical compositions and to the production thereof.

La présente invention concerne un procédé de traitement ou de prévention de céphalées, de migraines ou de céphalées vasculaires de Horton. Ledit procédé consiste à administrer conjointement une quantité thérapeutique efficace d'un antagoniste de CGRP (A) ou d'un sel physiologiquement acceptable de celui-ci, et une quantité thérapeutique efficace d'un inhibiteur de recapatage de la sérotonine (B) ou d'un sel physiologiquement acceptable de celui-ci. L'invention concerne également les compositions pharmaceutiques correspondantes et leur fabrication.

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