Treatment of lower urinary tract symptoms associated with...

A - Human Necessities – 61 – K

Patent

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A61K 31/404 (2006.01) A61K 31/085 (2006.01) A61K 31/216 (2006.01) A61K 31/405 (2006.01) A61K 31/407 (2006.01) A61K 31/415 (2006.01) A61K 31/4174 (2006.01) A61K 31/4178 (2006.01) A61K 31/451 (2006.01) A61K 31/4523 (2006.01) A61K 31/453 (2006.01) A61K 31/454 (2006.01) A61K 31/4706 (2006.01) A61K 31/517 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2494210

This invention relates to pharmaceutical combinations suitable for treating the lower urinary tract symptoms associated with either overactive bladder or mild to moderate benign prostatic hyperplasia, which combinations contain an alpha-adrenoceptor antagonist and a 5-HT4 antagonist. The combinations of the invention are particularly suitable for treating moderate or severe symptomatology.

Cette invention a trait à des combinaisons pharmaceutiques des mieux adaptées au traitement de symptômes des voies urinaires basses liés à une hyperactivité ou à une activité modérée de la vessie et ce, afin d'atténuer une hyperplasie prostatique bénigne. Ces combinaisons contiennent un antagoniste du récepteur adrénergique alpha ainsi qu'un antagoniste de la sérotonine-4 (5-HT¿4?). Les combinaisons selon l'invention se révèlent des mieux adaptées s'agissant de traiter des symptômes modérés ou aigus.

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