Methods and compositions for the sustained release of chromium

A - Human Necessities – 61 – K

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A61K 33/24 (2006.01) A61K 9/52 (2006.01) A61P 3/10 (2006.01)

Patent

CA 2681158

Provided herein are compositions for the administration of chromium that include at least two components: a hydrophilic chromium complex and a lipophilic chromium complex, and methods of using the same. Also provided are compositions for the administration of chromium that include a first "fast-acting" chromium complex and a second "slow-acting" chromium complex, wherein the first chromium complex is absorbed more quickly than the slow-acting chromium complex, and methods of using the same. Also provided herein are methods for treating, preventing, and improving conditions associated with cardiometabolic syndrome, by identifying a subject in need of treatment, prevention, or improvement of a condition associated with cardiometabolic syndrome, and providing a therapeutically effective amount of a composition comprising a fast-acting chromium complex and a slow-acting chromium complex, to the individual.

Cette invention a trait à des compositions utilisées pour administrer du chrome et comprenant au moins deux composants : un complexe à base de chrome hydrophile et un complexe à base de chrome lipophile, ainsi que des procédés permettant de les utiliser. L'invention concerne également des compositions utilisées pour administrer du chrome et comprenant un premier complexe à base de chrome <= à action rapide >= et un second complexe à base de chrome <= à action lente >=, ledit premier complexe à base de chrome étant absorbé plus rapidement que le complexe à base de chrome à action lente, ainsi que des procédés permettant de les utiliser. L'invention concerne par ailleurs des procédés permettant de traiter, de prévenir et d'améliorer des affections associées avec le syndrome cardiométabolique, en identifiant un sujet nécessitant un traitement, une protection ou une amélioration d'une affection associée avec le syndrome cardiométabolique, et permettant d'apporter au sujet une quantité thérapeutiquement efficace d'une composition comprenant un complexe à base de chrome à action rapide et un complexe à base de chrome à action lente.

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