C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/02 (2006.01) B01J 19/00 (2006.01) C12M 1/34 (2006.01) G01N 21/62 (2006.01) G01N 21/64 (2006.01) G01N 21/66 (2006.01) G01N 33/483 (2006.01) G01N 33/50 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2257287
The present invention discloses devices and methods of performing high- throughput screening of the physiological response of cells to biologically active compounds and methods of combining high-throughput with high-content spatial information at the cellular and subcellular level as well as temporal information about changes in physiological, biochemical and molecular activities. The present invention allows multiple types of cell interactions to be studied simultaneously by combining multicolor luminescence reading, microfluidic delivery, and environmental control of living cells in non- uniform micro-patterned arrays.
Dispositifs et procédés permettant d'effecter un criblage à haute capacité de la réponse physiologique de cellules à des composés à activité biologique, et procédés permettant de combiner une haute capacité avec des informations spatiales à haute densité aux niveaux cellulaire ou subcellulaire, ainsi que des informations temporelles sur des modifications des activités physiologiques, biochimiques et moléculaires. La présente invention permet d'étudier des types multiples d'interactions cellulaires simultanément en combinant les relevés de luminescence multicolore, l'apport microfluidique et le contrôle de l'environnement des cellules vivantes dans des groupements non uniformes à micro-configuration.
Biodx Inc.
Mbm & Co.
LandOfFree
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