Oxime derivatives and their use as pharmaceutically active...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 409/12 (2006.01) A61K 31/38 (2006.01) A61K 31/44 (2006.01) A61P 35/00 (2006.01) C07D 333/38 (2006.01)

Patent

CA 2519301

Objects of the present invention are the compounds of formula I, their pharmaceutically acceptable salts as well as their enantiomeric forms, diastereoisomers and racemates; the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds as inhibitors of histone deacetylase ( HDAC ) and therefore in the control or prevention of illnesses and disorders as mentioned above, or in the manufacture of corresponding medicaments.

La présente invention a trait à des composés de formule I, leurs sels pharmaceutiquement acceptables ainsi que leurs formes énantiomériques, leurs diastéréisomères et leurs racémates. L'invention a également trait à la préparation desdits composés, des médicaments les contenant et leur fabrication, ainsi que l'utilisation desdits composés en tant qu'inhibiteurs d'histone déacétylase et donc dans le contrôle ou la prévention de maladies et de troubles mentionnés dans la description, ou dans la fabrication de médicaments correspondants.

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