Mutated acvr1 for diagnosis and treatment of fibrodyplasia...

Details Mutated acvr1 for diagnosis and treatment of fibrodyplasia... Mutated acvr1 for diagnosis and treatment of fibrodyplasia...

C - Chemistry, Metallurgy

12

N

C12N 15/16 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 31/7105 (2006.01) A61K 31/713 (2006.01) A61K 48/00 (2006.01) C07H 21/00 (2006.01) C07K 14/72 (2006.01) C07K 16/28 (2006.01) C12N 15/12 (2006.01) C12P 19/34 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/563 (2006.01) G01N 33/566 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2649770

This invention is directed to mutated Activin A type I receptor proteins (ACVR1) and isolated nucleic acids encoding same. The invention also relates to the use of mutated ACVR1 in the diagnosis and treatment of Fibrodysplasia Ossificans Progressiva (FOP).

L'invention concerne des protéines mutantes du récepteur de l'activine A de type I (ACVR1) et des acides nucléiques isolés codant pour ce récepteur. L'invention se rapporte également à l'utilisation de ces ACVR1 mutants pour le diagnostic et le traitement de la fibrodysplasie ossifiante progressive (FOP).

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