2-aminocarbonyl-quinoline compounds as platelet adenosine...

Details 2-aminocarbonyl-quinoline compounds as platelet adenosine... 2-aminocarbonyl-quinoline compounds as platelet adenosine...

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/496 (2006.01) A61P 7/02 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2507657

Compounds of formula (I), where m, n, R1, R2, R3, R4 and R6 are described herein, are useful as inhibitors of platelet adenosine diphosphate. Pharmaceutical compositions containing these compounds, methods of using these compounds as antithrombotic agents and processes for synthesizing these compounds are also described herein.

La présente invention concerne des composés de formules (I) dans laquelle m, n, R?1¿, R?2¿, R?3¿, R?4¿et R?6¿ ont les correspondances indiquées, qui sont utiles comme inhibiteurs de l'adénosine diphosphate des plaquettes. L'invention a également pour objet des compositions pharmaceutiques contenant ces composés, des procédés pour les utiliser en tant qu'agents antithrombotiques, et des procédés pour synthétiser ces composés.

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