Use of heme-containing proteins as stabilizers for...

Details Use of heme-containing proteins as stabilizers for... Use of heme-containing proteins as stabilizers for...

G - Physics

01

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167/45

G01N 33/544 (2006.01) G01N 33/535 (2006.01) G01N 33/543 (2006.01) G01N 33/571 (2006.01) G01N 33/76 (2006.01)

Patent

CA 2040837

-0- USE OF HEME-CONTAINING PROTEINS AS STABILIZERS FOR ENZYME-LABELED IMMUNOREACTANTS Abstract of the Disclosure Heme-containing proteins, such as cytochrome c, are useful in admixture with enzyme-labeled immunoreactants, such as peroxidase-labeled antibodies or fragments thereof. The heme-containing proteins and enzyme-labeled immunoreactants can be supplied in a buffered composition as part of a test kit. The buffered composition comprising the heme-containing protein and peroxidase-labeled immunoreactant excludes 4'-hydroxyacetanilide, which is a phenolic electron transfer agent. The composition can be used in immunoassays for detecting various immunologically reactive species, such as hCG, and chlamydial or gonococcal antigens.

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