Inhibitors of checkpoint kinases

Details Inhibitors of checkpoint kinases Inhibitors of checkpoint kinases

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4745 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2635361

The instant invention provides for compounds which comprise fused pyrazoles that inhibit CHK1 activity. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting CHK1 activity by administering the compound to a patient in need of treatment of cancer.

La présente invention concerne des composés comprenant des pyrazoles condensés qui inhibent l~activité CHK1. L~invention concerne également des compositions comprenant de tels composés inhibiteurs et des procédés d~inhibition de l~activité CHK1 par administration du composé à un patient nécessitant un traitement du cancer.

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