Process for the preparation of a liposome dispersion under...

Details Process for the preparation of a liposome dispersion under... Process for the preparation of a liposome dispersion under...

A - Human Necessities

61

K

A61K 9/127 (2006.01) A61K 31/555 (2006.01) B01F 17/14 (2006.01) B01J 13/02 (2006.01)

Patent

CA 2119610

The invention relates to a novel, advantageous process for the preparation of liposomes for the inclusion of water-soluble or hydrophilic substances or mixtures of substances, which process provides the surprising advantage, in comparison with known processes, that the proportion of substances or mixtures of substances actually included is increased and which, when used pharmaceutically, provides the advantage of sterile working conditions. In this process, a mixture consisting of at least one phospholipid and customary lipophilic excipients is subjected to a mobile carrier phase consisting of carbon dioxide and a polar organic solvent (modifier) under supercritical pressure and temperature conditions, the compressed mixed phase is reduced to normal pressure and transferred to an aqueous phase comprising a substance having water-soluble or hydrophilic properties for encapsulation in liposomes.

Affiliated with

Also associated with

Rating

Process for the preparation of a liposome dispersion under... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of a liposome dispersion under..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of a liposome dispersion under... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1471215