G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/68 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2546130
The present invention relates to cell-based assays useful for screening for modulators, such as inhibitors, of activated mutant KIT tyrosine kinase receptors, which are associated with mast cell-related disorders, such as mastocytosis and various types of cancer. The invention further provides for the treatment of mast cell-related disorders with an inhibitor identified by the screening method.
La présente invention concerne des essais à base de cellules convenant à la recherche systématique de modulateurs, notamment d'inhibiteurs, de récepteurs rendus actifs de tyrosine kinase KIT mutante, qui sont associés à des troubles en relation avec les cellules basophiles, et notamment la mastocytose. L'invention concerne également le traitement de tels troubles avec un inhibiteur identifié par le procédé de l'invention.
Andreev Julian
Arkinstall Stephen J.
Blume-Jensen Peter
Dong Rong
Healey Brian
Applied Research Systems Ars Holding N.v.
Kirby Eades Gale Baker
LandOfFree
Methods for identifying modulators of active kit tyrosine... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Methods for identifying modulators of active kit tyrosine..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Methods for identifying modulators of active kit tyrosine... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1471445