A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/14 (2006.01) A01N 25/26 (2006.01) A61K 9/10 (2006.01) A61K 9/107 (2006.01)
Patent
CA 2211262
The present invention relates to micellar nanoparticles and methods of their production. Micellar nanoparticles are made by hydrating a mixture of an oil, a stabilizer/surfactant, and an alcoholic initiator with an aqueous solution. These micellar nanoparticles are normally less than 100 nanometers in diameter. The micellar nanoparticles are particularly advantageous in delivering materials such as estradiol topically through the skin because their small size allows easy penetration.
La présente invention a pour objet des nanoparticules micellaires, ainsi que leurs procédés de production. On fabrique ces nanoparticules micellaires en hydratant un mélange d'une huile, d'un agent stabilisant/tensioactif et d'un agent d'amorçage à base d'alcool avec une solution aqueuse. Ces nanoparticules micellaires présentent généralement un diamètre inférieur à 100 nanomètres. Elles conviennent particulièrement à l'apport de matières telles que l'estradiol par voie topique à travers la peau, dans la mesure où leur faible dimension facilite leur pénétration.
Wright D. Craig
Graceway Pharmaceuticals Llc
Novavax Inc.
Riches Mckenzie & Herbert Llp
LandOfFree
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