Tissue protective cytokines for the protection, restoration,...

Details Tissue protective cytokines for the protection, restoration,... Tissue protective cytokines for the protection, restoration,...

A - Human Necessities

61

K

A61K 38/19 (2006.01) A61K 31/00 (2006.01) A61K 38/18 (2006.01) A61K 45/00 (2006.01) A61K 45/06 (2006.01) A61P 29/00 (2006.01) C07K 14/505 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2491406

Methods and compositions are provided for treating a mammal having inflammation by protecting or enhancing a responsive cell, tissue, organ or body part exhibiting or associated with the inflammation, by systemic or local administration of a composition comprising a tissue protective cytokine. The invention also encompasses combination treatments comprising administering a composition comprising a tissue protective cytokine of the invention and administering at least one anti-inflammatory or least one immunomodulatory agent.

L'invention concerne des méthodes et des compositions permettant de traiter un mammifère soufrant d'une inflammation par la protection ou la stimulation d'une cellule, d'un tissu, d'un organe ou d'une partie du corps sensibles présentant l'inflammation ou associés à cette dernière puis par l'administration systémique ou locale d'une composition contenant une cytokine de protection tissulaire. Cette invention concerne également des traitements combinés consistant à administrer une composition contenant cette cytokine de protection tissulaire puis à administrer au moins un agent anti-inflammatoire ou au moins un agent immunomodulateur.

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