Human epo mimetic hinge core mimetibodies, compositions,...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 38/18 (2006.01) C07H 21/04 (2006.01) C07K 14/435 (2006.01) C07K 14/505 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2540665

The present invention relates to at least one novel human EPO mimetic hinge core mimetibody or specified portion or variant, including isolated nucleic acids that encode at least one EPO mimetic hinge core mimetibody or specified portion or variant, EPO mimetic hinge core mimetibody or specified portion or variants, vectors, host cells, transgenic animals or plants, and methods of making and using thereof, including therapeutic compositions, methods and devices.

La présente invention concerne au moins un nouveau miméticorps de noyau charnière mimétique de l'EPO humaine ou leur partie ou variante correspondante, y compris des acides nucléiques isolés qui codent pour au moins un miméticorps de noyau charnière mimétique de l'EPO ou leur partie ou variante correspondante, un miméticorps de noyau charnière mimetique de l'EPO ou sa partie ou variante correspondante, des vecteurs, des cellules hôtes, des animaux ou des plantes transgéniques, et des procédés de leur fabrication et de leur utilisation, y compris les compositions thérapeutiques, ainsi que des procédés et dispositifs correspondants.

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