High-molecular-weight adiponectin measurement method

Details High-molecular-weight adiponectin measurement method High-molecular-weight adiponectin measurement method

G - Physics

01

N

G01N 33/53 (2006.01) A61K 38/22 (2006.01) A61P 3/10 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) C12Q 1/37 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2716852

Provided is a method of separating and measuring highly active HMW adiponectin in adiponectin multimers. A method of measuring high-molecular-weight adiponectin in a sample, wherein adiponectin multimers are separated by use of a protease and measured immunologically, the method comprising reacting a sample containing adiponectin multimers with chymotrypsin.

L'invention porte sur un procédé pour fractionner et mesurer une adiponectine de masse moléculaire élevée hautement active dans de l'adiponectine multimère. Il s'agit d'un procédé de mesure immunologique qui utilise des protéases pour fractionner de l'adiponectine multimère afin de mesurer de l'adiponectine de masse moléculaire élevée dans des échantillons, et qui est caractérisé par le fait qu'il permet à de la chymotrypsine d'agir sur des échantillons comprenant de l'adiponectine multimère.

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