Process to prepare taxol

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 417/12 (2006.01) C07C 231/14 (2006.01) C07C 233/83 (2006.01) C07C 233/87 (2006.01) C07C 237/20 (2006.01) C07C 255/44 (2006.01) C07C 257/06 (2006.01) C07C 271/22 (2006.01) C07C 311/19 (2006.01) C07D 263/04 (2006.01) C07D 263/06 (2006.01) C07D 277/80 (2006.01) C07D 285/125 (2006.01) C07D 305/14 (2006.01) C07D 307/68 (2006.01) C07D 309/12 (2006.01) C07D 333/38 (2006.01) C07D 413/12 (2006.01) C07F 7/10 (2006.01) C07F 7/18 (2006.01) C08L 67/07 (2006.01) C12P 7/42 (2006.01) C12P 41/00 (2006.01) C07C 251/44 (

Patent

CA 2251703

The present invention includes processes to prepare commercially important taxols (X) from substituted amino-3-phenyl (2R, 3S) isoserinates (II). In addition processes to prepare the substituted amino-3-phenyl (2R, 3S) insoserinates (II) as well as its precursor are set forth.

La présent invention comprends des procédés de préparation de taxols répondant à la formule (X) et importants sur le plan commercial, à partir d'amino-3-phényl(2R,3S)isosérinates (II) substituées. En outre, on décrit des procédés de préparation d'amino-3-phényl(2R,3S)isosérinates (II) substituées et du précurseur de celles-ci.

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