Novel applications for staphylococcus aureus sbi protein

Details Novel applications for staphylococcus aureus sbi protein Novel applications for staphylococcus aureus sbi protein

C - Chemistry, Metallurgy

07

K

C07K 14/31 (2006.01)

Patent

CA 2653668

The invention relates to the Sbi protein of Staphylococcus aureus. It has been found that Sbi can bind to the C3 complement protein and various proteolytic fragments thereof and consequently is able to inhibit the three complement pathways (i.e. the classical pathway, the alternative pathway and the lectin pathway). The invention therefore provides methods and compositions for inhibition of the complement system and for treatment of inflammatory conditions characterised by undesirable activation of the complement pathway.

L'invention concerne la protéine Sbi de Staphylococcus aureus. Il s'est avéré que la protéine Sbi peut se fixer au complément C3 et à des fragments protéolytiques de celui-ci et qu'elle est capable, par conséquent, d'inhiber les trois voies d'activation du complément (c'est-à-dire la voie classique d'activation, la voie alternative d'activation et la voie de la lectine). Ainsi, l'invention concerne des procédés et des compositions destinés à l'inhibition du système du complément et au traitement de troubles inflammatoires se caractérisant par une activation indésirable de la voie d'activation du complément.

Affiliated with

Also associated with

Rating

Novel applications for staphylococcus aureus sbi protein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Novel applications for staphylococcus aureus sbi protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel applications for staphylococcus aureus sbi protein will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1475332