Human pf4a receptors and their use

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/28 (2006.01) A61K 39/395 (2006.01) C07K 14/705 (2006.01) C12N 15/12 (2006.01)

Patent

CA 2407304

-49- cDNAs encoding a class of novel PF4ARs has been identified in human tissue. Provided herein are nucleic acid sequences of three PF4ARs (including the human Il-8 receptor) useful as a diagnostic and in the recombinant preparation of PF4ARs. The PF4ARs are used in the preparation and purification of antibodies capable of binding to the receptors, and in diagnostic essays.

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