C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/06 (2006.01) A61K 38/05 (2006.01) C07D 401/12 (2006.01) C07D 409/12 (2006.01) C07D 417/12 (2006.01) C07D 419/12 (2006.01) C07K 5/065 (2006.01) G01N 33/94 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2262818
The invention concerns modified aminoacids of general formula (I) in which A, Z, X, n, m, R, R2, R3, R4 and R11 are defined in claims 1 through 5, their tautomers, their diastereomers, their enantiomers, their mixtures and their salts, specially their physiologically compatible salts with inorganic or organic acids or bases, pharmaceuticals containing these compounds, their use and the method for their production, as well as their use for the production and purification of antibodies and as marked compounds in RIA and ELISA assays and as diagnostic or analytic auxiliary agents in neurotransmitter research.
La présente invention concerne des aminoacides modifiés correspondant à la formule générale (I), dans laquelle, A, Z, X, n, m, R, R?2¿, R?3¿, R?4¿ et R?11¿ correspondent à la définition donnée dans les revendications 1 à 5, ainsi que leurs tautomères, leurs diastéromères, leurs énantiomères, leurs mélanges et leurs sels, en particulier leurs sels physiologiquement compatibles, avec des acides ou des bases inorganiques ou organiques, des médicaments contenant ces composés. L'invention concerne également l'utilisation de ces composés et leur procédé de production, ainsi que leur utilisation pour la production et la purification d'anticorps, comme composés marqués pour effectuer des dosages radio-immunologiques et des tests ELISA, et comme agents auxiliaires de diagnostic et d'analyse dans la recherche relatives aux neurotransmetteurs.
Doods Henri
Eberlein Wolfgang
Engel Wolfhard
Entzeroth Michael
Hallermayer Gerhard
Dr. Karl Thomae Gesellschaft Mit Beschrankter Haftung
Fetherstonhaugh & Co.
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