Viral particles which are released after the infection with...

Details Viral particles which are released after the infection with... Viral particles which are released after the infection with...

C - Chemistry, Metallurgy

12

N

C12N 7/00 (2006.01) A61K 39/245 (2006.01) A61P 31/22 (2006.01) C07K 14/045 (2006.01) C12N 7/04 (2006.01) C12N 15/38 (2006.01) C12N 15/869 (2006.01)

Patent

CA 2365903

The invention relates to viral particles which are released by mammal cells after the infection with the human cytomegalovirus (HCMV). The invention also relates to particles whose antigenicity has been optimised by changing the HMCV using genetic engineering. The invention further relates to the use of such particles as a vaccine and to a method for multiplying the HCMV in mammal cells.

L'invention concerne des particules virales qui sont libérées par les cellules de mammifères après infection par le virus cytomégalique humain (HCMV). L'invention concerne également des particules dont l'antigénicité a été optimisée par la modification génétique du virus HCMV. L'invention concerne enfin l'utilisation de telles particules comme vaccin et un procédé de multiplication du HCMV dans les cellules de mammifères.

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