Aryl and heteroaryl fused imidazo (1,5-a) pyrazines as...

Details Aryl and heteroaryl fused imidazo (1,5-a) pyrazines as... Aryl and heteroaryl fused imidazo (1,5-a) pyrazines as...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/4985 (2006.01) A61P 25/18 (2006.01)

Patent

CA 2706986

The invention relates to imidazo[1,5-a]pyrazine derivatives, to processes for preparing them, to pharmaceutical preparations which comprise these compounds and to the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase (PDE10), as active compounds for treating central nervous system diseases of mammals, including humans.

L'invention porte sur des dérivés d'imidazo[1,5-a]pyrazine, sur des procédés permettant de les préparer, sur des préparations pharmaceutiques qui comprennent ces composés et sur l'utilisation pharmaceutique de ces composés, qui sont des inhibiteurs de la phosphodiestérase 10 (PDE10), comme composés actifs pour traiter des maladies du système nerveux central de mammifères, y compris les êtres humains.

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