Pyrimidinediamine kinase inhibitors

Details Pyrimidinediamine kinase inhibitors Pyrimidinediamine kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 413/14 (2006.01)

Patent

CA 2746810

The present invention provides pyrimidinediamine compounds useful for inhibiting kinase activity, including the activity of polo-like kinase 1 (PLK1). Also provided are pharmaceutical compositions comprising these compounds and methods of treating diseases associated with kinase activity, in particular enhanced PLK1 catalytic activity, such as diseases associated with abnormal cell proliferation, including neoplastic disorders.

La présente invention porte sur des composés pyrimidinediamines utiles pour inhiber une activité kinase, comprenant l'activité de la kinase 1 de type polo (PLK1). L'invention porte également sur des compositions pharmaceutiques comprenant ces composés et sur des procédés de traitement de maladies associées à une activité kinase, en particulier une activité catalytique PLK1 accrue, telles que des maladies associées à une prolifération cellulaire anormale, comprenant des troubles néoplasiques.

Affiliated with

Also associated with

Rating

Pyrimidinediamine kinase inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pyrimidinediamine kinase inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrimidinediamine kinase inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1482745