Preparation of 3-fluoro oxindole derivatives

Details Preparation of 3-fluoro oxindole derivatives Preparation of 3-fluoro oxindole derivatives

C - Chemistry, Metallurgy

07

C

C07C 205/56 (2006.01) C07C 201/16 (2006.01) C07D 209/34 (2006.01) A61K 31/404 (2006.01)

Patent

CA 2267947

The present invention relates to novel itermediates of formula (1) wherein the wavy bond (- -) represents the racemate, the (R)-enantiomer or the (S)-enantiomer; and R is hydrogen, a carboxyl-protecting group or a cation of an addition salt; or solvate thereof; and to the use thereof in a process for the preparation of certain 3-fluoro oxindole derivatives.

L'invention concerne de nouveaux intermédiaires représentés par la formule (1) dans laquelle la liaison ondulée ( SIMILAR SIMILAR ) représente le racémate, le (R)-énantiomère ou le (S)-énantiomère; R représente hydrogène, un groupe carboxyle protecteur ou un cation d'un sel d'apport; ou un de ses solvates; ainsi que leur utilisation dans un procédé de préparation de certains dérivés de 3-fluoro oxindole.

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