Process for preparing carboxylic acids by carbonylation of...

C - Chemistry – Metallurgy – 07 – C

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C07C 57/30 (2006.01) C07C 51/12 (2006.01) C07C 57/58 (2006.01) C07C 59/64 (2006.01) C07C 59/76 (2006.01) C07C 67/37 (2006.01) C07C 69/612 (2006.01) C07C 251/44 (2006.01) C07D 207/20 (2006.01) C07D 209/34 (2006.01) C07D 213/75 (2006.01) C07D 263/57 (2006.01) C07D 279/22 (2006.01) C07D 333/24 (2006.01) C07D 337/14 (2006.01)

Patent

CA 2182212

A new process for preparing aryl-substituted aliphatic carboxylic acids is provided. Aryl-substituted aliphatic ether or thioether compound is reacted with carbon monoxide in aqueous conditions at a temperature between 25°C ad 200°C. An acid such as hydrochloric acid may be added. As catalyst, a mixture of palladium or a palladium compound and a copper compound with at least one acid-stable ligand are present.

Nouveau procédé de préparation d'acides carboxyliques aliphatiques à substitution aryle. On fait réagir un composé éther ou thioéther aliphatique à substitution aryle avec du monoxyde de carbone dans des conditions aqueuses à une température entre 25 ~C et 200 ~C. On peut ajouter un acide tel que l'acide chlorhydrique. Comme catalyseur, on utilise un mélange de palladium ou d'un composé de palladium, et d'un composé de cuivre avec au moins un ligand résistant aux acides.

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