Compositions of and treatment with biologically active...

Details Compositions of and treatment with biologically active... Compositions of and treatment with biologically active...

C - Chemistry, Metallurgy

07

K

C07K 14/46 (2006.01) A61K 38/17 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2042468

ABSTRACT OF THE DISCLOSURE A biologically active peptide wherein each amino acid residue of the peptide is a D-amino acid residue or a glycine residue. Examples of such peptides wherein each amino acid residue is a D-amino acid residue or a glycine residue include deletion and substitution analogues of magainin peptides, CPF peptides, PGLa peptide, XPF peptide, and derivatives of cholecystokinin. Such peptides have increased resistance to proteolytic enzymes while retaining biological activity.

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