Methods and compositions for identifying, classifying and...

Details Methods and compositions for identifying, classifying and... Methods and compositions for identifying, classifying and...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2751293

The invention is directed to methods and kits that allow for identifying, classifying, and monitoring cancer patients for Bcl-2 family inhibitor therapies. The methods and compositions of the invention are directed to determining amplification of BcI-XL and in cancer or tumor cells, or elevated BcI-X L polypeptide expression.

L'invention concerne des procédés et des trousses permettant d'identifier, de classer et de surveiller des patients cancéreux dans le cadre de thérapies aux inhibiteurs de la famille Bcl-2. Les procédés et compositions de l'invention visent à déterminer l'amplification de BCI-XL dans des cellules cancéreuses ou tumorales, ou une expression élevée de polypeptides de BCI-XL.

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