Vascular hypertrophy suppressor

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/66 (2006.01) A61K 31/395 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/415 (2006.01) A61K 31/422 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/53 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2115985

Abstract of the Disclosure This invention relates to a vascular hypertrophy suppressor comprising as an active ingredient a compound represented by the formula: Image wherein ring W is a nitrogen-containing heterocyclic ring residue which may be substituted; R1 is hydrogen or an optionally substituted hydrocarbon residue which optionally binds through a hetero-atom; R3 represents a group capable of forming an anion or a group capable of changing thereto; X shows that the phenylene and phenyl groups bind to each other directly or through a spacer having an atomic length of two or less; n denotes 1 or 2; a and b forming the heterocyclic ring residue are independently one or two optionally substituted carbon or hetero atoms; c is an optionally substituted carbon or hetero atom; provided that, when the ring W is a condensed ring, R1 is hydrogen or an optionally substituted hydrocarbon residue which binds through a hetero atom, or a salt thereof.

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