Bone substitution material and a method of its manufacture

C - Chemistry – Metallurgy – 01 – B

Patent

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Details

C01B 25/32 (2006.01) A61F 2/28 (2006.01) A61F 2/30 (2006.01) A61K 9/20 (2006.01) A61L 24/02 (2006.01) A61L 27/00 (2006.01) A61L 27/12 (2006.01) A61L 27/38 (2006.01) A61L 27/42 (2006.01) C01B 25/16 (2006.01) A61F 2/00 (2006.01) A61F 2/02 (2006.01) A61F 2/46 (2006.01)

Patent

CA 2220306

The present invention provides a process for converting a standard inert amorphous calcium phosphate precipitate into highly reactive amorphous solids. The amorphous solids can be used to react with other calcium phosphate solids to form a poorly-crystalline synthetic hydroxyapatite that provides both bioactivity and structural integrity. This novel amorphous material can be reacted with other calcium phosphates at or below 37 °C to form a bone-like material consisting of poorly cyrstalline hydroxyapatite.

La présente invention concerne un nouveau processus permettant de transformer un précipité de phosphate de calcium amorphe et inerte classique en solides amorphes hautement réactifs. Ces solides amorphes peuvent être utilisés pour entrer en réaction avec d'autres solides de phosphate de calcium afin de former une hydroxyapatite synthétique peu cristalline qui ait à la fois une bioactivité ainsi qu'une intégrité structurelle. Ce nouveau matériau amorphe peut être mis en réaction avec d'autres phosphates de calcium à une température inférieure ou égale à 37 DEG C de manière à former un matériau similaire à l'os et se composant d'hydroxyapatite peu cristalline.

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