A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 41/00 (2006.01) A61K 31/185 (2006.01) A61K 31/54 (2006.01) A61K 31/5415 (2006.01)
Patent
CA 2401624
The invention relates to a method of photoeradication of cellular and acellular organisms including the steps of providing a surface acting agent in association with a cellular or acellular organism, the surface acting agent disorienting a membrane structure so that said membrane no longer functions as an effective osmotic barrier; providing a photosensitive material in association with the cellular or acellular organism; and applying light in association with the cellular or acellular organism to cause a disruption of the organism. The method according to the present invention may be utilized in invitro and invivo treatment protocols for infections, sterilization procedures, cancer cell eradication, virus and fungus eradication, spore eradication, and biofilm organism eradication. Additional aspects of the invention include particular combinations of photosensitive materials and surfactants for use in photodynamic therapies.
L'invention concerne un procédé de photo-éradication d'organismes acellulaires et cellulaires, comprenant les étapes suivantes consistant à préparer un agent tensioactif, en association avec un organisme acellulaire ou cellulaire, cet agent désorientant une structure membranaire, de façon que la membrane ne fonctionne plus en tant que barrière osmotique efficace, à préparer un matériau photosensible, en association avec l'organisme acellulaire ou cellulaire, puis à appliquer de la lumière sur cet organisme acellulaire ou cellulaire, de manière à provoquer une rupture de celui-ci. On peut utiliser le procédé de l'invention dans des protocoles de traitement, in vitro ou in vivo, d'infections, dans des procédures de stérilisation et dans l'éradication de cellules cancéreuses, virus, champignons, spores et organismes mucilages. D'autres aspects de l'invention concernent des combinaisons particulières de matériaux photosensibles et de tensioactifs, destinées à des thérapies photodynamiques.
Biel Merrill A.
Advanced Photodynamic Technologies Inc.
Goudreau Gage Dubuc
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