Hydrophilic/lipophilic polymeric matrix dosage formulation

Details Hydrophilic/lipophilic polymeric matrix dosage formulation Hydrophilic/lipophilic polymeric matrix dosage formulation

A - Human Necessities

61

K

A61K 9/24 (2006.01) A61K 9/20 (2006.01) A61K 31/4045 (2006.01) A61K 31/506 (2006.01) A61K 31/5377 (2006.01) A61P 25/16 (2006.01)

Patent

CA 2405508

An oral dosage form comprising a pharmaceutical tablet of one or more layers, one of which carries a biologically active substance; the formulation of said tablet includes different percentages of hydrophilic and lipophilic polymeric materials, and adjuvant substances. The tablets of the present invention show a release rate which is independent from the amounts of active substance present in the tablet.

L'invention concerne une forme posologique orale constituée d'un comprimé pharmaceutique comprenant une ou plusieurs couches, l'une desdites couches renfermant une substance biologiquement active. La formulation dudit comprimé comprend différents pourcentages de matières polymères hydrophiles et lipophiles et de substances adjuvantes. Les comprimés selon la présente invention présentent une vitesse de libération indépendante de la quantité de substance active contenue dans le comprimé.

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