Pyrazole-amine compounds for the treatment of...

Details Pyrazole-amine compounds for the treatment of... Pyrazole-amine compounds for the treatment of...

C - Chemistry, Metallurgy

07

D

C07D 231/40 (2006.01) A61K 31/415 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2561441

The present invention relates to compounds of the Formula (I) wherein R1, R3, R4, R5, R6, R7 and R8 are as defined. Compounds of the Formula (I) have activity inhibiting production of A.beta.-peptide. The invention also relates to pharmaceutical compositions and methods of treating disorders and diseases, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of the Formula (I).

L'invention concerne des composés de formule (I), dans laquelle R1, R3, R4, R5, R6, R7 et R8 sont tels que définis dans la description. Ces composés de formule (I) présentent une activité inhibant la production de peptide A.beta.. L'invention concerne également des compositions pharmaceutiques contenant lesdits composés, ainsi que des méthodes de traitement de divers troubles et maladies, notamment les troubles neurodégénératifs et/ou neurologiques, la maladie d'Alzheimer par exemple, chez un mammifère.

Affiliated with

Also associated with

Rating

Pyrazole-amine compounds for the treatment of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pyrazole-amine compounds for the treatment of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrazole-amine compounds for the treatment of... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1489592