Bioadhesive-wound healing composition

A - Human Necessities – 61 – K

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Details

A61K 45/06 (2006.01) A61K 31/355 (2006.01) A61Q 11/00 (2006.01)

Patent

CA 2194876

The present invention pertains to therapeutic bioadhesive-wound healing compositions useful for treating wounds and increasing the proliferation and resuscitation rate of mammalian cells. The compositions comprise a bioadhesive agent and a therapeutically effective amount of a wound healing composition. In one embodiment the wound healing composition comprises (a) pyruvate; (b) an antioxidant; and (c) a mixture of saturated and unsaturated fatty acids. The therapeutic bioadhesive-wound healing compositions may further comprise medicaments such as antiviral agents, antikeratolytic agents, anti- inflammatory agents, antifungal agents, antibacterial agents, immunostimulating agents, and the like. The bioadhesive-wound healing compositions may be utilized in a wide variety of pharmaceutical products. This invention also relates to methods for preparing and using the bioadhesive- wound healing compositions and the pharmaceutical products in which the compositions may be used.

L'invention concerne des compositions thérapeutiques, bioadhésives, cicatrisantes, utiles pour traiter des plaies et augmenter la vitesse de prolifération et de reconstitution des cellules de mammifères. Ces compositions comprennent un agent bioadhésif ainsi qu'une quantité, efficace sur le plan thérapeutique, d'une composition cicatrisante. Dans un mode de réalisation, cette composition comprend: (a) du pyruvate; (b) un antioxydant, et (c) un mélange d'acides gras saturés et insaturés. Ces compositions peuvent en outre comprendre des médicaments tels que des agents antiviraux, antikératolytiques, anti-inflammatoires, antifongiques, antibactériens, immunostimulants et analogues. On peut utiliser ces compositions dans une large gamme de produits pharmaceutiques. L'invention concerne également des procédés de préparation et d'utilisation de ces compositions bioadhésives cicatrisantes ainsi que les produits pharmaceutiques dans lesquels on peut utiliser celles-ci.

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